O3 Plus, LLC
About O3 Plus, LLC
Located in San Antonio, Texas, O3 Plus, LLC is a specialized health and wellness clinic dedicated to medical ozone therapy and regenerative treatments. Founded in February 2014 by Dr. Francis W. Mueller, MD, the practice blends decades of family medicine expertise with cutting‑edge ozone research to offer a holistic, non‑surgical approach to healing. The clinic’s mission is to augment traditional medicine with complementary therapies that amplify recovery and overall vitality. O3 Plus delivers a comprehensive suite of regenerative services that target musculoskeletal disorders and chronic systemic conditions. Patients benefit from ozone therapy, intravenous nutritional infusions, and a range of injection techniques—including Prolozone, Platelet‑Rich‑Plasma (PRP) injections, Neural Therapy, and Exosome Therapy—to promote tissue regeneration and pain relief. Hyperbaric oxygen therapy, UV light treatment, and specialized modalities such as limb bagging, insufflations, and topical ozone applications further expand the practice’s ability to address knee, hip, shoulder, spine, elbow, and ankle & foot concerns while supporting immune balance and metabolic health. The clinic emphasizes individualized, evidence‑based protocols that prioritize non‑invasive, non‑surgical joint pain relief and overall wellness. The authority of O3 Plus is reinforced by the credentials and experience of its core team. Dr. Francis W. Mueller, MD, a board‑certified family physician with over 27 years of clinical practice, leads the practice as its founding physician and a recognized pioneer in medical ozone therapy. Nurse Practitioner Kimberly Engelman, MSN, APRN, FNP‑BC, brings a decade of injection expertise and advanced nursing education to patient care. Together, they have cultivated affiliations with professional societies such as the American Academy of Ozonotherapy and the Institute of Functional Medicine, and they regularly present research at national conferences, underscoring O3 Plus’s commitment to innovation and excellence in regenerative orthopedics.
